Endocrine Abstracts

69-year-old male, with a history of bipolar disorder under treatment, smoker and high blood pressure. He is referred for left adrenal injury detected incidentally by secondary hypertension study. Abdominal CT shows a mass of 67.7×51.8×52.3 mm in the left adrenal area, with radiological characteristics of malignancy and aggressive behavior, contacting the left renal pole and upper splenic pole, compatible with adrenal carcinoma vs. metastasis. The functional study is ...

A 38-year-old transsexual woman, with no known drug allergies, active tobacco smoker, ICAT 2. As diseases of interest, stage A2 human immunodeficiency virus (HIV) infection with current negative viral load. Lúes in 2012 treated. In treatment with Stribild (elvitegravir 150 mg/ cobicistat 150 mg/ emtricitabine 200 mg/ tenofovir disoproxil fumarate 245 mg). She went to the Transsexual Persons Care Unit due to gender inconsistency since childhood with the adoption of the fem...

A 36-year-old woman in follow-up due to early ovarian failure of idiopathic origin. No family history of interest. History of menarche at 12 years of age with regular menses until 18 years of age, when it begins with amenorrheic spells lasting up to 8 months. Laboratory tests revealed hypergonadotropic hypogonadism with negative ovarian autoantibodies, normal karyotype, and gynecological ultrasound showing a normal-looking uterus with slight bilateral ovarian atrophy. Negative...

Introduction: Demand for health care for transsexual people has increased exponentially in last years, especially among adolescents and young adults. Gender-affirming hormones (GAHs) are initiated to accommodate secondary sexual characteristics to the desired sex. Published studies about metabolic repercussion of GAHs are heterogeneous and report diverse results. Our objective is to evaluate the effect of GAHs on cardiovascular risk factors in transsexual population treated in...

Introduction: There have been more than 130 genes described in relation with the development of obesity, which condition hyperphagia and early obesity. The aim of this study is to determine the prevalence of genetic alterations in a cohort of patients with morbid obesity.Materials and Methods: We designed a descriptive cross-sectional study for a cohort of subjects with obesity grade III or higher (BMI ≥40 kg/m2), treated at endocrinolog...

The relationship between gestational diabetes mellitus (GDM) and oxidative stress is not well known and the effect of oxidative stress in GDM placenta and the impact that could have on perinatal morbidity and risk of future complications is also yet to be elucidated. The aim of the study was to evaluate the relationships between maternal and placental tissue levels of markers of oxidative stress and antioxidants in women with GDM, which potentially may have considerable clinic...

Introduction: Insulinomas are pancreatic neuroendocrine tumors (PNET), characterized by insulin hypersecretion syndrome with the development of hypoglycemia. The incidence of the tumor is 3-10 cases per million inhabitants. The average age of onset is 40-50 years old, being more frequent in women. Case Reports: We present a clinical case of a patient with CREST syndrome and difficult-to-control hypoglycemia. Female patient, 81 years old, with a history o...

Gestational diabetes mellitus (GDM) is associated with an increased risk of pregnancy-induced hypertension (PIH). Ambulatory blood pressure monitoring (ABPM) has been used to screen for PIH and preeclampsia in normotensive type 1 diabetic women. To date, there are no data regarding ABPM in women with GDM. The aim of the study was to establish blood pressure (BP) profiles for pregnant with GDM, using ABPM and determine whether a BP pattern can define a population at risk for de...

Objective: To evaluate in our area BICI therapy efficacy in pregestational type 1 diabetes.Methods: We conducted a descriptive retrospective analysis studying metabolic control and obstetrics results in patients with pregestational type 1 diabetes, treated with BICI between 2004 and 2012 in our hospital.Results: We evaluated 28 patients with type 1 diabetes and diabetes duration of 17.3±6.6 years. In 27.3% of patients the trea...

Methods: Retrospective and descriptive study in a sample of 36 patients with suspected hypoglycemia who were admitted to our Service to perform a 72-hour fasting test. Demographic, clinical data and results of fasting test were analyzed. Endogenous hyperinsulinism criteria were considered to be the combination of plasma glucose <55 mg dl, insulin >3 mcrU / ml and C peptide > 0.6 ng/ml, in the absence of detection of sulfonylureas.Results: The...